I am trying to implement 2 factor authentication to Exchange Server 2010 SP3 OWA. This is on premises. I need the proper documentation so that I can properly implement this solution.

[ShawnRobinson]

I am trying to implement 2 factor authentication to Exchange Server 2010 SP3 OWA. This is on premises. I need the proper documentation so that I can properly implement this solution.

[EdwardDavis]

Check here: under Microsoft

https://community.rsa.com/docs/DOC-106364 

In general if you have Authentication Manager (you have not indicated what you have on premise) and OWA is on IIS, then you install RSA Agent for IIS 8.0.3 and follow the implementation guide to set it up as an agent.